FREQUENCY OF HAEMOPHILIA AND BLEEDING PARAMETERS OF PERSON’S WITH BLEEDING DISORDERS IN SOUTH EAST NIGERIA

FREQUENCY OF HAEMOPHILIA AND BLEEDING PARAMETERS OF PERSON’S WITH BLEEDING DISORDERS IN SOUTH EAST NIGERIA

ABSTRACT

A significant number of people living with haemophilia are reported to be either under-diagnosed or mismanaged in most developing countries. This may results in increase in disease related morbidity and mortality in childhood. The aim of this study is to evaluate the frequency of haemophilia and bleeding parameters of tghose with bleeding disorders in South East Nigeria. Fifty consecutive consenting persons with bleeding disorder that met inclusion criteria were recruited from the four tertiary hospitals in South East Nigeria. Blood samples were collected for full blood count, coagulation screening test and Factor VIII assays. Data was analyzed using the graph pad prism version 6. Results obtained from this study showed that 2% of subjects with bleeding disorder has haemophilia and they are within mild range, the most common bleeding symptoms is gastrointestinal bleeding (23.4%) and the most common bleeding score was four (32.4%) was obtained from subjects with bleeding disorders in South East Nigeria. Furthermore, this study also showed that thrombocytopaenia (68%) was found in subjects with bleeding disorders. These results showed that haemophilia may not be under-diagnosed as earlier suggested by other authors. However, it may be necessary to screen for Factor VIII in cases of bleeding when indicated. Further studies may be needed to determine the likely causes of thrombocytopaenia in bleeding disorders in our environment.