Department: Zoology Project Topics and Materials

OXIDATIVE STRESS BIOMARKERS, HAEMATOLOGICAL PARAMETERS AND HISTOPATHOLOGICAL CHANGES IN THE AFRICAN CATFISH, Clarias gariepinus EXPOSED TO AN ORGANOPHOSPHATE PESTICIDE, FENTHION ABSTRACT In the present study, specimens of Clarias gariepinus having mean weight and standard length of 197.38 ± 2.34 g and 27.36 ± 0.23 cm respectively were exposed to an organophosphate pesticide, fenthion. The median …

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PATHOPHYSIOLOGICAL EFFECT OF AQUEOUS EXTRACT OF MORINGA OLEIFERA LEAVES ON CLARIAS GARIEPINUS CHALLENGED WITH ICHTHYOPHTHIRIUS MULTIFILLIS ABSTRACT Icthyophthirius multifilis (Ich), a dangerous ectoparasite causes white spot disease and economic losses in fish farms. A majority of the chemotherapeutic agents of ichthyophthiriasis are either pollutants of the environment, banned or lack efficacy. The present work was …

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PATHOPHYSIOLOGICAL EFFECTS OF IRVINGIA GABONENSISIRVINGIA WOMBOLU SEED POWDERS COMBINATIONS ON ALLOXAN-INDUCED DIABETIC MALE RATS. ABSTRACT This study aimed at investigating the pathophysiological effects of crude seed powders of Irvingia gabonensis and Irvingia wombolu combined in different proportions on alloxan-induced diabetic rats. Both species of Irvingia were analysed for phytochemical content. A total of 72 male …

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PLASMA BIOCHEMISTRY, HAEMATOLOGICAL AND BIOMETRIC PARAMETERS OF PROTOPTERUS ANNECTENS OF ANAMBRA RIVER, NIGERIA ABSTRACT Biochemical, haematological and biometric  studies of the African lungfish, Protopterus annectens were carried out in order to establish their mean and reference values which would serve as baseline data for assessment of the health status of the fish as well as …

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PLASMA LIPID, SERUM PROTEIN AND BODY MASS INDICES AMONG Plasmodium falciparum MALARIA-INFECTED WOMEN ATTENDING ANTENATAL CLINICS IN IGBO-EZE NORTH LOCAL GOVERNMENT AREA, ENUGU STATE. ABSTRACT A cross-sectional study on the plasma lipid, serum protein and body mass indices of Plasmodium falciparum-malaria infected women attending antenatal clinics in Igbo-Eze North Local Government Area, Enugu State, Nigeria …

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PLASMODIUM FALCIPARUM AND GASTROINTESTINAL HELMINTH CO-INFECTION AMONG PRIMARY SCHOOL CHILDREN IN UZO-UWANI LOCAL GOVERNMENT AREA, ENUGU STATE ABSTRACT This study determined the Plasmodium falciparum (P. falciparum) and gastrointestinal helminths co-infection among school children in Uzo-Uwani Local Government Area of Enugu State. Blood and stool samples were collected from 218 school children of ages 7 -18 …

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POPULATION DYNAMICS OF CICHLID FISH SPECIES OF OPI LAKE, NSUKKA. ENUGU STATE, NIGERIA. ABSTRACT Studies on the population dynamics of cichlid fish species in Opi lake were carried out between August, 2014 and January, 2015. Also, physico-chemical parameters of the lake were analyzed using appropriate methods. Morphometric relationships and seasonal variations of the fish species …

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PREVALENCE OF BOVINE CYSTICERCOSIS AND FASCIOLIASIS IN SLAUGHTERED CATTLE IN NSUKKA ZONE AND THE HAEMATOLOGICAL, BIOCHEMICAL AND HISTOPATHOLOGICAL CHANGES IN RESPONSE TO ACTIVE INFECTION ABSTRACT The prevalence and distribution of bovine cysticercosis and fascioliasis in cattle slaughtered in Nsukka zone, together with the haematological, biochemical and histopathological aspects of active infection were investigated from April …

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PREVALENCE OF HYPOGLYCAEMIA AMONG Plasmodium falciparum INFECTED WOMEN ATTENDING ANTENATAL CLINICS IN NSUKKA LOCAL GOVERNMENT AREA OF ENUGU STATE, NIGERIA ABSTRACT Hypoglycaemia prevalence among Plasmodium falciparum infected women attending antenatal clinics in Nsukka Local Government Area of Enugu State, Nigeria was undertaken. The study objective was to assess the prevalence of hypoglycaemia and P. falciparum …

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SCREENING FOR in vitro ACTIVITY OF EXTRACTS OF Picralima nitida AGAINST Plasmodium falciparum. ABSTRACT         The intolerable impact of malaria has been attributed to the increasing resistance of Plasmodium parasite to chemoprophylactic and chemotherapeutic agents. The need for drugs with novel modes of action prompted this research, to discover a new anti-malaria agent from this …

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STUDIES ON URINARY PHENOL LEVELS IN SCHISTOSOMA HAEMATOBIUM INFECTED INDIVIDUALS IN ABAKALIKI, EBONYI STATE AND ITS RELATIONSHIP TO DISEASE SEVERITY. ABSTRACT This study was carried out to determine urinary phenol levels of individuals with Schistosoma haematobium infection and the possible relationship with parasite egg output and intensity of infection. An initial base line study was …

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STUDY ON WATER QUALITY PARAMETERS AND BENTHIC FAUNA DIVERSITY OF OTAMIRI RIVER IN OWERRI, IMO STATE, NIGERIA. ABSTRACT The study on the physic-chemical parameters and benthic fauna diversity of Otamiri River, Nigeria was carried out from June to December 2015. Water and benthic organisms samples were collected monthly from three sampling stations along the stream. …

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THE PREVALENCE OF PARASITE CONTAMINATION OF VEGETABLES AND THE RISK FACTORS IN THEIR TRANSMISSION IN NSUKKA ECOLOGICAL ZONE, ENUGU STATE ABSTRACT The prevalence of parasite contamination of vegetables and the risk factors in their transmission were investigated in Nsukka Ecological Zone, Enugu State, Nigeria. A total of four hundred and eighty-eight (488) samples of six …

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EFFECT OF LEAF EXTRACTS OF PSIDIUM GUAJAVA (GUAVA) ON THE BIOCHEMICAL AND HAEMATOLOGICAL INDICES OF ALBINO RATS ABSTRACT This study was to investigate the effect of aqueous and methanolic extracts of Psidium guajava leaves on the biochemical and haematological indices of liver functions in rats, and compare the effect of the extracts on body weight …

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EFFECT OF PARASITE INFESTATION ON THE BIOCHEMICAL AND HAEMATOLOGICAL CHARACTERISTICS OF SOME CLARIID (SILIRUFORMES) SPECIES OF THE ANAMBRA RIVER SYSTEM OF NIGERIA ABSTRACT A study based on monthly sampling of catches in Anambra river system (Otuocha station) was carried out between May 2013 and April 2014 to investigate the parasitofauna of wild clariid catfishes with …

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EFFECTS OF AQUEOUS LEAF EXTRACTS OF LORANTHUS MICRANTHUS LINN. (LORANTHACEAE) ON BIOCHEMICAL AND HAEMATOLOGICAL PROFILES OF ALBINO RATS INFECTED WITH TRYPANOSOMA BRUCEI BRUCEI Abstract The effects of oral administration of aqueous crude seed extracts  of Loranthus micranthus on the biochemical and haematological  parameters of albino rats infected with Trypanosoma brucei brucei were investigated for 28days. …

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EFFECTS OF GONGRONEMA LATIFOLIA AND OCIMUM GRATISSIMUM COMBINED AQUEOUS EXTRACTS ON ALLOXAN-INDUCED DIABETIC RATTUS NOVERGICUS ABSTRACT The effect of combined aqueous leaves extracts of O. gratissimum and G. latifolium on alloxan-induced diabetic Rattusnorvegicuswas investigated for 28 days. Lethal dose (LD50) and phytochemical compositions were determined by standard methods. A total of 90 rats were divided …

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EFFECTS OF MANAGEMENTS OF MALARIA ON HAEMATOLOGICAL BIOCHEMICAL AND NUTRITIONAL CHANGES IN CHILDREN IN ANAMBRA STATE, NIGERIA ABSTRACT This study investigated the effects of home (community) and hospital management of childhood malaria on the prevalence, haematology, biochemical and nutritional indices of malaria parasite infected children in Anambra State, Nigeria. It also evaluated the knowledge, attitude …

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EPIDEMIOLOGY AND TRANSMISSION PATTERNS OF Schistosoma haematobium INFECTIONS IN CENTRAL EBONYI STATE, NIGERIA. ABSTRACT Study on epidemiology and transmission patterns of Schistosoma haematobium infections were carried out between July, 2013 and April, 2014 in 16 out of 47 communities making up Ebonyi Central zone Ebonyi State, Nigeria. This is to determine the prevalence of Schistosoma …

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EPIDEMIOLOGY OF GASTRO-INTESTINAL HELMINTH INFECTION OF GOATS IN NSUKKA URBAN ABSTRACT Gastro-intestinal helminth infection of goats in Nsukka Urban was investigated to determine the parasites prevalence and intensity. Faecal samples were collected from the abattoir located at Ikpa community Market. Samples were analyzed using direct smear and concentration methods. Single and mixed infection of the …

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EPIDEMIOLOGY, CHEMOTHERAPY OF ONCHOCERCIASIS AND DEVELOPMENT OF ONCHOCERCA-SPECIFIC POLYMERASE CHAIN REACTION BASED ON A P-GLYCOPROTEIN GENE. ABSTRACT Onchocerciasis is a disease caused by a filarial nematode Onchocerca volvulus, which is transmitted to man through the bite of infected black flies of the Simulium damnosum complex.  In Achi community (South Eastern Nigeria) – ivermectin treatments started …

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LABORATORY EVALUATION OF ETHANOLIC EXTRACTS OF GARLIC (Allium sativum) CLOVES AND Aloe vera LEAVES AS PROTECTANTS AGAINST THE MAIZE WEEVIL, Sitophilus zeamais ABSTRACT This study evaluated the efficacy of ethanolic extracts of Allium sativum (Woodwill) cloves, Aloe vera (Miller) leaves and their mixture against Sitophilus zeamais (Motschulsky) under laboratory conditions. Experiments were carried out to …

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MASS PRODUCTION OF ROTIFER (BRANCHIONUSCALYCIFLORUS) FOR AQUACULTURE ABSTRACT Mass production of freshwater rotifer, Branchionuscalyciflorus was carried out using different food types (Chlorella sp., Spirulina sp., and Baker’s yeast). Rotifer stock culture was prepared using NPK + urea (50g: 2.5g) and chicken droppings with freshly grown alga. Different food concentrations (150, 300, 650 and 1000 mg/ml) …

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ANTI-DIABETIC PROPERTIES OF N-HEXANE FRUIT EXTRACT OF DACRYODES EDULIS ON ALLOXAN-INDUCED DIABETIC RATS (RATTUS NOVERGICUS) ABSTRACT The present study was undertaken to investigate the anti-diabetic properties of n-hexane extract of Dacryodes edulis on alloxan-induced diabetic rats. A total of 24 and 72 adult albino rats were used for the acute (24 hours) and sub-chronic (15 …

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ANTI-OBESITY PROPERTIES OF ETHANOLIC SEED EXTRACT OF SPHENOSTYLIS STENOCARPA ON HIGH FAT DIET-INDUCED OBESED RATS (RATTUS NORVEGICUS) ABSTRACT The anti-obesity properties of ethanolic extract of Sphenostylis stenocarpa on high fat diet-induced obese rats was investigated for a period of 28 days. A total of 72 adult albino rats were used for the study. The rats …

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ASPECTS OF HISTOPATHOLOGICAL EFFECTS OF HIBISCUS SABDARIFFA EXTRACTS ON ALBINO RATS ABSTRACT The effect of oral administration of aqueous and methanolic extracts of dried calyx of Hibiscus sabdariffa on the histological features of some tissues of Rattus norvegicus was studied for a period of 28 days. One hundred and eight (108) adult male and female …

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ASSESSMENT OF THE LEVELS OF LACTATE DEHYDROGENASES IN MALARIA INFECTION AND ITS EFFECTS ON ACRIDINE ORANGE STAINING DURING DIAGNOSIS IN PATIENTS FROM NGWO, UDI LGA IN ENUGU ABSTRACT Malaria is a potential medical emergency and should be treated accordingly. Delays in diagnosis and treatment are leading causes of death in many countries. The availability of …

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ASSESSMENT OF THE ROLE OF MALARIA IN THE AETIOLOGY OF RENAL IMPAIRMENT IN ISU COMMUNITY IN EBONYI STATE, NIGERIA ABSTRACT This study, the involvement of malaria in renal impairment among individuals in selected villages of Isu community in Onicha Local Government Area of Ebonyi State was investigated. A two-stage sampling design was adopted in which …

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COMMUNITY-BASED DIAGNOSIS AND MANAGEMENT OF CHILDHOOD MALARIA USING RAPID DIAGNOSTIC TEST AND MANAGEMENT WITH ARTEMISININ –BASED COMBINATION THERAPY IN TARABA STATE-NIGERIA ABSTRACT A cross-sectional study was conducted for fifteen (15) months (May, 2012 to July, 2013) to assess the efficacy of Rapid Diagnostic Test (RDT) in diagnosis followed by treatment of childhood malaria with Artemisinin …

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COMPARATIVE EVALUATION OF Cymbopogon citratus STAPF LEAF EXTRACT AS SEEDS PROTECTANT AGAINST Sitophilus zeamais MOTSCHULSKY (COLEOPTERA CURCULIONIDAE) ON STORED MAIZE (Zea mays L.) ABSTRACT A study was conducted to determine the efficacy of extracts of Cymbopogon citratus (Stapf) as post harvest protectants of maize seeds against Sitophilus zeamais Motsch, field to store insect pest of …

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ECOLOGY OF AQUATIC INSECTS IN OPI LAKE, ENUGU STATE, NIGERIA. ABSTRACT The ecology of aquatic insects of Opi Lake was carried out to determine their composition, abundance and diversity from February to July, 2014. Adult insects of different species were collected from the water surface using a dip-net with Nytex® netting of 500µm mesh. In …

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ECTO AND INTESTINAL ENDO-PARASITIC FAUNA OF BUSHMEAT IN NSUKKA ECOLOGICAL ZONE, NIGERIA ABSTRACT A study was carried out between December 2012 and July 2014 in Nsukka, Southeast Nigeria, with the aims of determining the prevalence, intensity and abundance of ecto and intestinal end-oparasitic fauna of bushmeat and evaluating bushmeat supplier’s knowledge, attitude about zoonotic wildlife …

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EFFECT OF CLIMATE CHANGE ON CLARIID FISHERIES RESOURCES OF KAINJI LAKE, NIGERIA ABSTRACT Climate change is believed to have major implication on agricultural production, fisheries resources and food security especially in the aquatic ecosystem of the sub-tropical and tropical regions. However, in Nigeria serious emphasis has not been paid on studying the impacts of this …

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ALGAL DIVERSITY AND WATER QUALITY OF ASATA RIVER ENUGU, ENUGU STATE, NIGERIA ABSTRACT An assessment of the physicochemical, parameters, algal diversity and bacterial flora of Asata River Enugu, Enugu State, Nigeria was carried out for six months. Water samples and periphyton were collected fortnightly from four locations namely: Okpara Coal Mine, University of Nigeria Teaching …

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