PRODUCTION OF Aspergillus niger GLUCOAMYLASE USING GUINEA CORN STARCH AMYLOPECTIN AS THE ONLY CARBON SOURCE ABSTRACT This study was aimed at the production of glucoamylase which can be utilised for starch hydrolysis. A fourteen days experimental study was carried out to determine the day of highest glucoamylase activity. Day five and day twelve of the …
PRODUCTION, PARTIAL PURIFICATION AND CHARACTERIZATION OF CELLULASE BY ASPERGILLUS NIGER FROM SUBMERGED FERMENTATION OF GRAPE BAGASSE ABSTRACT The increase in agricultural practices has necessitated the judicious use of agricultural wastes into value added products. In this study the ability of selected cellulosic substrate to induce cellulase production by Aspergillus niger and the ability of the …
PURIFICATION AND CHARACTERIZATION OF PAPAIN FROM CARICA PAPAYA LATEX ITS APPLICATION IN THE HYDROLYSIS OF TIGERNUT PROTEIN HOMOGENATE ABSTRACT In this study, the production of tiger nut suspension was carried out using a proteolytic enzyme (papain) isolated from the latex of C. papaya. The crude papain isolated was subjected to three steps purification system of …
RENAL BIOCHEMICAL CHANGES OF PREGNANCY-INDUCED HYPERTENSION IN PREGNANT WOMEN ATTENDING TERTIARY HOSPITALS IN ENUGU STATE ABSTRACT Pregnancy induced hypertensive disorders have become very common medical complication in Nigeria with its attendant morbidity and mortality. The morbidity and mortality may be associated with its possible effect on the kidneys which was studied. Results of the electrolyte …
SOME BIOCHEMICAL CHANGES IN HIV POSITIVE PATIENTS ON HIGHLY ACTIVE ANTIRETROVIRAL THERAPY ABSTRACT Some biological changes are observed during human immuno deficiency virus (HIV) infection. Once CD4+ count decreases to 500 cells/mm3 highly active antiretroviral therapy (HAART) is initiated. This work, seeks to elucidate the effect of HAART on some of the biochemical changes caused …
STUDIES ON THE ACTIVITY OF ∞-AMYLASE PRODUCED FROM Fusarium spp. USING SWEET POTATO (Ipomoea batatas) STARCH. ABSTRACT After a seven day pilot studies, day 6 was found suitable for enzyme production from Fusarium species using starch from Ipomoea batatas (sweet potato) tubers as the carbon source. The specific activity of the crude enzyme was 55.45µ/mg. …
STUDIES ON THE EFFECT OF AQUEOUS EXTRACT OF MILLETTIA ABOENSIS LEAVES ON LOMOTIL – INDUCED CONSTIPATION IN WISTAR ALBINO RATS ABSTRACT Millettia aboensis leaf is a rich source of reducing sugar, tannins, glycosides and flavonoids and has been reported to have medicinal property as well as some physiological potentials. The leaf also has been used …
STUDIES ON THE PHYTOCHEMICAL AND NUTRITIONAL COMPOSITION OF AQUEOUS LEAF EXTRACT OF JUSTICIA CARNEA AND ITS EFFECT ON SOME BIOCHEMICAL PARAMETERS IN ANAEMIC RATS. ABSTRACT Anaemia is a common blood disorder that affects people of all ages, though people at greater risk are the elderly, young women and infants. Different drugs are used but many …
SURVEY OF SODIUM, POTASSIUM, IRON AND CALCIUM CONTENTS OF RETAIL SAMPLES OF SOME PROCESSED FOODS (BREAKFAST CEREALS AND SNACKS) SOLD IN NSUKKA, ENUGU STATE ABSTRACT Processed foods have been noted to be generally, high in sodium but, low in potassium. Some of these foods such as snacks often provide a quick bite at work and …
THE EFFECTS OF ALCOHOL ADMINISTRATION ON SERUM LIPID PROFILE, TOTAL PROTEIN AND LIVER ENZYMES IN RATS ABSTRACT Alcohol has many biological actions, and adverse effects on lipid metabolism. The main objective of this present study was designed to study the effects of alcohol administration on serum lipid profile, total protein, liver enzymes and histopathological effect …
TOXIC PROFILE OF THE METHANOL LEAF EXTRACT OF Senna siamea AND ITS ANTIOXIDANT PRPOPERTIES ABSTRACT Medicinal plants have been assumed to be good in detoxifications because they contain bioactive compounds capable of doing this. However, some plants are very toxic to both humans and animals with the potential of damaging certain organs in the body. …
THERMODYNAMICS AND KINETICS OF THERMO-INACTIVATION AND REGENERATION OF PARTIALLY PURIFIED PEROXIDASE FROM Gongronema latifolium LEAVES. ABSTRACT Peroxidase activity from G. latifolium was done to see whether it could be used in industries. Crude peroxidase was extracted from G. latifolium with 0.05M sodium phosphate buffer of pH 6.0; 70% ammonium sulphate saturation to precipitated protein with …
THE INTERACTION OF THE ANTIMALARIAL DRUGS (ARTEMETHER AND LUMEFANTRINE) WITH HAEMOGLOBIN A AND S A UV- VISIBLE STUDY ABSTRACT On the premise that the resistance of malaria is related to the structure of the sickle haemoglobin molecule, a comparative denaturation of haemoglobin A (HbA), haemoglobin AS (HbAS) and haemoglobin S (HbS) in their relaxed states …
MODELING GENETIC DEFECTS AS A MOLECULAR BIOMARKER IN EVALUATING ENVIRONMENTAL IMPACTS DICHLORVOS ON PULLET CHICKS ABSTRACT Environmental pollution and poisoning owing to the widespread use of pesticides in agricultural and domestic pest control may be detrimental to the health of handlers, non target organisms and consumers. In this study, genetic defect was used as a …
MODULATION OF HIGH FRUCTOSE FED, STREPTOZOTOCIN-INDUCED TYPE 2 DIABETES BY WONDERFUL KOLA (BUCHHOLZIA CORIACEA) SEED EXTRACTS IN MALE WISTAR RATS ABSTRACT Type 2 diabetes (T2D) occurs when there is an advanced determent in insulin action (insulin resistance, IR), which proceeds toβ-cell dysfunction. This present study assessed the modulatory effects of Buchholziacoriacea(B. coriacea) seeds extract …
NUTRIENT COMPOSITION OF YEAST BIOFORTIFIED AKAMU ABSTRACT The nutrient composition of yeast biofortified akamu, a cereal-based fermented food was determined using two different concentrations of inocula preparations at 5% and 10% glucose concentrations. While keeping the peptone and yeast extract constant at 2% and 1% respectively. These media were used to inoculate the akamu at …
OXIDATIVE STRESS AND MITOCHONDRIAL DYSFUNCTION IN HUMAN IMMUNODEFICIENCY VIRUS PATIENTS ON HIGHLY ACTIVE ANTIRETROVIRAL THERAPY ABSTRACT This study was aimed at evaluating oxidative stress and mitochondrial dysfunction in HIV patients on a combination of emtricitabine, tenofovir and efavirenz (ATRIPLA), commonly used for treating these patients attending the HIV clinic of Enugu State University Teaching (ESUT) …
PARTIAL PURIFICATION AND CHARACTERIZATION OF AMYLASE FROM GERMINATED AFRICAN YAM BEAN SEEDS (Sphenostylis stenocarpa) ABSTRACT The activity of α-amylase and protein concentration in African yam bean seeds increases as germination progresses up to day 8 of germination where it exhibited its highest level, followed by sequenced decreased activity and protein concentration till day 12. Starch …
PH AND THERMAL STABILITIES OF PEROXIDASE ISOLATED FROM RIPENING TOMATO FRUITS (SONALUM LYCOPERSICON) ABSTRACT Peroxidase (EC 1.11.1.7) extracted from Sonalum lycopersicon was purified, on a two-step purification process of ammonium sulphate precipitation and gel filtration. The specific activity of the crude enzyme was 55.45μ/mg. The crude enzyme was purified to the level of gel filtration …
PHYTOCHEMICAL, ANTIOXIDANT AND TOXICOLOGICAL PROPERTIES OF METHANOL EXTRACT OF PHYLLANTHUS AMARUS ABSTRACT The use of medicinal plants for the treatment of many diseases is associated with folk medicine from different parts of the World. However, information on the toxicology of these plants part used in Nigeria folk medicine is rare. Thus, this work is aimed …
PHYTOCHEMICALS, ANTIOXIDANTS AND TOXICOLOGICAL PROPERTIES OF METHANOL EXTRACT OF SECURIDACA LONGEPEDUNCULATA ABSTRACT One of the problems associated with medicinal plants in Nigeria is paucity of information on the phytochemistry and toxicity of some of these plants. The study aimed at revealing a range of phytochemicals in the plant, which are physiologically potent in ameliorating several …
PREVALENCE AND SEVERITY OF HYPOGLYCAEMIA AND LACTIC ACIDOSIS IN CHILDREN DIAGNOSED WITH Plasmodium falciparum MALARIA ABSTRACT The prevalence and severitay of hypoglycaemia and lactic acidosis in Nigerian children diagnosed with Plasmodium falciparum malaria were determined in 100 outpatient children aged 3-144 months (12 years). The children were grouped into 2 categories: 3-59 month old and …
PRODUCTION AND OPTIMIZATION OF GLUCOAMYLASES FROM PLANTS AND Aspergillusniger FOR STARCH HYDROLYSIS IN A BATCH BIOREACTOR ABSTRACT Glucoamylases were produced from both plants and microorganisms and were optimized for starch hydrolysis in batch bioreactor. Amylase activity was monitored in germinating guinea corn seeds for seven days. Highest amylase activity was observed on days 3 and …
EVALUATION OF NUTRIENT COMPOSITION AND ANTIOXIDANT PROPERTIES OF SELECTED COMMONLY CONSUMED AND UNDERUTILISED SEASONAL FRUITS IN NSUKKA METROPOLIS ABSTRACT The increased interest in antioxidant activity of plant phytochemicals has necessitated their determination in rarely consumed fruits. The aim of this study was to determine the antioxidant capacity as well as the vitamin and mineral content …
EVALUATION OF NUTRITIVE AND NON-NUTRITIVE COMPONENTS AND ANTI-DIABETIC PROPERTIES OF EDIBLE PORTIONS OF Chrysophyllumalbidum FRUIT IN STREPTOZOTOCIN INDUCED DIABETIC MALE ALBINO RATS ABSTRACT Diabetes is becoming a pandemic disease despite the recent surge in new drugs to manage the condition. The limitations of currently available oral anti-diabetic agents either in terms of efficacy/safety coupled …
EXTRACTION AND CHARACTERIZATION OF MANGANESE PEROXIDASE (MNP) FROM Rigidoporuslignosus, A WHITE ROOT ROT FUNGI OF RUBBER TREE. ABSTRACT This study was carried out to screen, partially purify and characterize Manganese peroxidase from Rigidoporuslignosus. This study started with the optimization of enzymes production in the laboratory scale of submerged fermentation system.A pilot study was carried out …
Garcinia kolaHeckel STEM BARK ETHANOLIC EXTRACT AND ITS TRITERPENOID FRACTION PROTECTED AGAINST SODIUM ARSENITE-INDUCED HEPATOTOXICITY AND NEPHROTOXICITY IN RAT MODELS ABSTRACT Arsenite is an environmental toxicant known to elicit adverse effects on liver and kidney organs. This study was designed to investigate the protective effects of Garcinia kola Heckel stem bark ethanolic extract (EEGK) and …
GLYCAEMIC INDICES OF MAIZE, ACHA, WHEAT AND OAT IN WISTAR RATS ABSTRACT This study was conducted to measure the glycemic index and blood glucose response of staple foods consumed in Nigeria in healthy Wistar rats. The test food samples Maize (Zea mays), Wheat (Triticum spp), Acha (Digitaria exilis) and Oat (Elkris super oat) were formulated …
IMPACT OF FRESH AND FERMENTED PALM OIL MILL EFFLUENTS ON SOIL PHYSICOCHEMICAL PARAMETERS AND ENZYME ACTIVITIES IN UMUAKA, NJABA, IMO STATE OF NIGERIA ABSTRACT ………………………….. The impact of palm oil mill effluents (POME) on soil fertility was determined by studying the physico-chemical and heavy metals parameters found in fresh and fermented POME from six palm …
ISOLATION, PARTIAL PURIFICATION AND CHARACTERIZATION OF GLUCOAMYLASE FROM Aspergillus niger IN SUBMERGED FERMENTATION USING AMYLOPECTIN FROM TIGER NUT STARCH AS CARBON SOURCE ABSTRACT Glucoamylase was isolated from Aspergillus niger and purified using ammonium sulphate precipitation and gel filtration respectively. The purified enzyme was then characterized to determine the optimum conditions required by the produced enzyme. …
ISOLATION, PARTIAL PURIFICATION AND CHARACTERIZATION OF α-AMYLASE FROM Bacillus alcalophilus ABSTRACT The aim of this study was to isolate, partially purify and characterize α-Amylase from Bacillus alcalophilus. The enzyme (α-amylase) was isolated from Bacillus alcalophilus using cassava as only carbon source. 20 g of soil sample were weighed out and dissolved in 40 ml of …
ISOLATION, PARTIAL PURIFICATION AND STABILITY STUDIES OF MANGANESE PEROXIDASE FROM WHITE ROT BASODIOMYCETES, Pleurotus tuber-Regium ABSTRACT Manganese peroxidase (MnP) enzyme is the most common lignin-modifying peroxidase produced by almost all wood-colonizing basidiomycetes causing white-rot and various soil-colonizing litter-decomposing fungi. Multiple forms of this glycosylated haeme protein with molecular weight normally at 40 to 50 kDa …
LIFE CYCLE ASSESSMENT OF THE ENVIRONMENTAL IMPACT OF BIOSURFACTANT PRODUCTION FROM OIL WASTE BY A DICULTURE OF AZOTOBACTER VINELANDII AND PSEUDOMONAS SP. ABSTRACT During the bioprocess of the biosurfactant production (by the consortium), the volume of CO2 evolved was 28.23 ± 5.08 cm3, which is equivalent to 0.056 ± 0.01g CO2 per 100 ml of …
EFFECT OF THE METHANOL EXTRACT OF JATROPHA TANJORENSIS LEAVES ON SOME HAEMATOLOGICAL AND ANTIOXIDANT PARAMETERS IN RATS ABSTRACT The effect of the methanol extract of Jatropha tanjorensis leaves on haematological and antioxidant parameters of rats was investigated. From the study, the percentage yield of the extract was 9.77%. The qualitative and quantitative phytochemical screening of …
EFFECT OF WATER ACTIVITY ON TRANSESTERIFICATION KINETIC PARAMETERS OF COCONUT OIL WITH ETHANOL ABSTRACT This work is focused on determining quantitatively how water, even in its smallest amount, affects transesterification kinetic parameters of coconut oil with ethanl; with the view of assessing whether it is preferable to use anhydrous ethanol with high price or ethanol …
EFFECTS OF ALCOHOL ON SOME BIOCHEMICAL PARAMETERS OF ALCOHOLICS IN NSUKKA, ENUGU STATE, NIGERIA ABSTRACT This work was aimed at finding the effects of alcohol on some biochemical parameters. A total of one hundred and eighty (180) apparently healthy, non-hypertensive male alcoholics were used for the study. Forty (40) non-consumers of alcohol were used as …
EFFECTS OF CHEMICALS USED IN STORING MAIZE ON IT S ZEIN CONTENT OVER A DURATION OF TIME ABSTRACT Maize is the largest and most important agricultural commodity in the world. Zein is the storage protein in maize known as prolamine. It is water insoluble and forms odorless, tasteless, clear edible films. The zein content of …
EFFECTS OF ETHANOL EXTRACTS OF EUPHORBIA HIRTA HERB ON SOME OXIDATIVE AND BIOCHEMICAL PARAMETERS IN ALLOXAN-INDUCED DIABETIC RATS ABSTRACT Diabetes mellitus produces a lot of highly reactive oxygen species which have been attributed to the aetiology and pathophysiology of the disease. In view of the adverse effects associated with synthetic drugs and natural medicine being …
EFFECTS OF METHANOL EXTRACT OF Chrysophyllum albidum SEEDS ON ALLOXAN- INDUCED-DIABETIC RATS ABSTRACT Methanol seed extract of Chrysophyllum albidum was studied to ascertain the potential effects of the extracts on some biochemical indices. The proximate composition of Chrysophyllum albidum seed methanol extract was found to contain crude protein (8.41± 0.02 mg/g), crude fat (19.12±0.01 mg/g), …
EFFECTS OF THIAMINE, PYRIDOXINE AND BIOTIN ON BLOOD GLUCOSE CONCENTRATION AND RENAL FUNCTION PARAMETERS OF ALLOXAN-INDUCED DIABETIC RATS ABSTRACT The aim of this study was to investigate the effects of thiamine, pyridoxine and biotin on the concentrations of blood glucose, serum electrolytes and renal functions of alloxan-induced diabetic rats. A total of twenty seven (27) …
ELUCIDATION OF SOME IMMUNOLOGICAL AND BIOCHEMICAL NATURE OF THE LEAVES OF SENNA MIMOSOIDES ABSTRACT In the present study, the phytochemical composition, immunomodulatory, leukocyte mobilization, haematological and antihepatotoxic effects of the aqueous extract of Senna mimosoides leaves were evaluated. The study also covered the effect of the extract on the activity of lactase and the assessment …
ESTIMATION OF DAILY SALT INTAKE OF HEALTHY AMBULANT NIGERIAN ADULTS ABSTRACT Data on the current levels of sodium consumption of Nigerian adults are urgently needed to determine the contribution of dietary sodium as a risk factor in the increasing incidence of hypertension and related complications in the country. The aim of this study was to …
ESTIMATION OF TOTAL PHENOLICS, TOTAL FLAVONOIDS AND IN VITRO ANTIOXIDANT ACTIVITIES OF METHANOL EXTRACT OF VOACANGA AFRICANA ROOT BARK AND ITS FRACTIONS ABSTRACT The in vitro antioxidant activities, total phenolic and flavonoid contents of the methanol extract of Voacanga africana root bark and the n-hexane, ethylacetate and n-butanol subfractions of the methanol extract were carried …
CHARACTERIZATION AND COMPARATIVE ASSESSMENT OF THE PHYSICO-CHEMICAL PROPERTIES OF COCONUT (Cocos nucifera) AND WALNUT (Tetracarpidium conophorum) OILS ABSTRACT Characterization and comparative assessment of Cocos nucifera and Tetracarpidium conophorum seeds and the oils were evaluated in this work using standard techniques. The percentage proximate analysis of the samples revealed that the moisture, ash, fibre and protein …
COMPARATIVE PROPERTIES OF THE METHYL AND ETHYL ESTERS PRODUCED FROM AVOCADO (Persea americana) PULP OIL ABSTRACT Biodiesel was produced from Avocado (Persea Americana) pulp oil by trans esterification with methanol and ethanol (6:1 methanol/ethanol-to-oil ratio) using 0.09% sodium hydroxide as catalyst in 60 minutes reaction time. The percentage yield of the methyl ester was 78% …
COMPARATIVE STUDIES ON THE EFFECTS OF DIFFERENT MODIFICATIONS ON THE COLD WATER SOLUBILITY OF STARCH FROM SELECTED UNDERUTILIZED LEGUMES ABSTRACT The industrial utilization of native starch is limited by its imperfect nature, hence the need for modifications. The continued use of conventional crops such as cassava, maize, rice and potato as sources of starch for …
COMPARATIVE STUDY OF THE EFFECTS OF AQUEOUS EXTRACTS OF MORINGA OLEIFERA AND VERNONIA AMYGDALINA LEAVES ON SOME BIOCHEMICAL INDICES IN ALBINO RATS ABSTRACT A comparative study of the effects of aqueous extract of Moringa oleifera and Vernonia amygdalina on selected biochemical indices of prostate pathologies of male albino rats was investigated using thirty two adult …
COMPARATIVE STUDY ON NUTRITIONAL COMPOSITION OF SOME BRANDS OF POPCORN COMMERCIALLY AVAILABLE IN ENUGU STATE, NIGERIA ABSTRACT This study was therefore designed to determine and compare the nutritional contents of some commonly consumed brands of popcorn snacks in unprocessed (uncooked) form of the cereal. Processed popcorn samples were procured from vendors at a movie theatre, …
DETERMINATION OF ELECTROLYTES AND GLYCOSYLATED HAEMOGLOBIN CONCENTRATIONS IN DIABETES MELLITUS PATIENTS IN GWAGWALADA AREA COUNCIL, ABUJA. ABSTRACT Diabetes is a major threat to global public health, and the numbers of diabetic patients are rapidly increasing world-wide. This study was aimed at determining the serum electrolyte concentration and glycosylated haemoglobin level of diabetic patients and apparently …
DETERMINATION OF LIPID PROFILE AND SOME BIOCHEMICAL INDICES IN PHYSICALLY ACTIVE AND SEDENTARY PREGNANT AND NON-PREGNANT WOMEN IN GIWA COMMUNITY, KADUNA STATE ABSTRACT Lipids and lipoproteins are essential constituents of the body and their activities assist in maintenance of the body homeostasis. Sedentary lifestyle, as predisposed by sedentary work has been shown to lead to …
DETERMINATION OF THYROID HORMONAL LEVELS IN HIV POSITIVE INDIVIDUALS IN NSUKKA COMMUNITY OF SOUTH EASTERN NIGERIA ABSTRACT This study assessed the levels of cluster determinant 4 (CD4+) cell, total protein, triacylglycerol (TAG), total cholesterol (TC), high density lipoprotein cholesterol (HDL-C), low density lipoprotein cholesterol (LDL-C), thyroid stimulating hormone (TSH) and thyroxine (T4), of one hundred …
EFFECT OF ALKALINE STEEP AND AIR-REST CYCLE ON THE DEVELOPMENT OF SORGHUM PEROXIDASE ACTIVITY DURING MALTING ABSTRACT The effect of alkaline steep and air-rest cycle on the development of peroxidase activity during malting was investigated in sorghum variety, KSV8. Preliminary experiment showed that alkaline steep (test) and the distilled water steep (control) had germinative energy …
EFFECT OF HONEY ON JEJUNUM AND PROSTATE SMOOTH MUSCLES OF RABBITS ABSTRACT Conventional chemotherapy has always taken a prominent place in dealing with diseased states; but owing to their various side-effects, natural products that play similar therapeutic roles have become the thrust of much research work. Hence, this study sought to investigate the possible reasons …
ANTI-INFLAMMATORY AND ANALGESIC ACTIVITIES OF CIPROFLOXACIN, LINCOMYCIN AND ERYTHROMYCIN IN WISTAR RATS ABSTRACT The effect of three antibiotics (ciprofloxacin, lincomycin and erythromycin) on the inflammatory process was studied both in vitro and in vivo. Agar-induced rat paw oedema was used as a model for acute inflammation, and the antibiotics were administered (10 mg/kg, 20 mg/kg …
ANTI-INFLAMMATORY AND HEPATOPROTECTIVE EFFECTS OF THE HOMOGENATE OF CUCUMIS SATIVUS (CUCUMBER) FRUITS ABSTRACT Research on inflammation has become the focus of global scientific study because of its implication in virtually all human and animal diseases. Also, liver diseases have been on increase and of global concern.Cucumis sativus is believed to have anti-oxidant activity, high flavonoid …
ANTIDIARRHOEAL EFFECT OF UNRIPE Musa paradisiacae PULP AND PEEL HOMOGENATES ON CASTOR OIL-INDUCED DIARRHOEA IN WISTAR ALBINO RATS ABSTRACT Musa paradisiacae commonly known as plantain is a rhizomatous perennial crop used as a source of starchy staple for millions of people in Nigeria. Different parts of the plant have been used in the treatment of …
ANTIMICROBIAL SCREENING AND ANTIINFLAMMATORY ACTIVITIES OF METHANOL EXTRACT OF Cissusaralioides ABSTRACT The aim of this study was to investigate the antimicrobial effect of Cissusaralioides extracts and their anti-inflammatory activity using experimental rat models. Phytochemical analyses of Cissusaralioides showed the presence of flavonoids, saponins, tannins, alkaloids, terpenoids, steroids and glycosides. Antimicrobial activity of C. aralioides was …
ANTIOXIDANT ACTIVITY, TOTAL PHENOLIC AND FLAVONOID CONTENTS OF WHOLE PLANT METHANOL EXTRACT AND SOLVENT FRACTIONS OF Desmodiumramosissimum G. Don ABSTRACT The present study was designed to estimate the total phenolic and flavonoid contents and to evaluate the in vitro antioxidant activities of both the methanol extract and the various solvent fractions of the whole plant, …
ANTIOXIDANT AND TOXICOLOGIC PROPERTIES OF METHANOL LEAF EXTRACT OF STEPHANIA DINKLAGEI IN WISTAR ALBINO RAT ABSTRACT Stephania dinklagei is used extensively in South East Nigeria for the traditional treatment of malaria and other associated ailments in form of decoction, in which unspecified quantities are usually consumed without due regards to toxicologic and other adverse effects. …
ANTIOXIDANT POTENTIAL OF DIFFERENT TYPES OF TEA ABSTRACT The present study evaluated the phytochemical constituents and in vitro antioxidant potential of different types of tea namely; black tea, un-caffeinated tea, green tea and herbal tea. Radical scavenging capacities of the tea extracts were determined using 2,2-diphenyl-2-picrylhydrazyl (DPPH) assay. Total antioxidant activity was determined using ferric …
BIOACCUMULATION AND RISK ASSESSMENT OF BUTACHLOR IN THE SOIL ECOSYSTEM ABSTRACT Bioaccumulation of butachlor in plants following its application in the farm against weeds was evaluated using Phaseolus vulgaris (bean plant). Also, the risk of the consumption of such plants with some amount of bioaccumulated butachlor by non-target humans was studied using rabbits as animal …
BIOCHEMICAL CHARACTERIZATION OF THE ANTIINFLAMMATORY CONSTITUENT AND ANTIOXIDANT ACTIVITY STUDIES ON STEM BARK EXTRACT OF CRATAEVA ADANSONII ABSTRACT In the last decade intensive research into the mechanisms of inflammation has implicated production of prostaglandins and reactive oxygen species as central to the progression of many inflammatory diseases. This study aimed at investigating/elucidating the biochemical mechanisms …
BIOCHEMICAL CHARACTERIZATION OF TOXIC CONSTITUENTS OF SEED EXTRACT OF AZADIRACHTA INDICA A. JUSS ABSTRACT The toxic constituents of seed extracts of Azadirachta indica A. Juss were isolated and biochemically characterised to elucidate the spectrum of toxicity. The constituents were isolated using toxicity-guided technique. Acute toxicity test established an oral LD50 >5 g/kg in mice. Chronic …
AESTIVATION INDUCTION AND EVIDENCE OF CONFORMATIONAL DIFFERENCES BETWEEN OXY-HAEMOCYANIN AND DEOXY-HAEMOCYANININ AESTIVATING AND NON-AESTIVATING SNAILS ABSTRACT Haemocyanin is a high molecular weight, dioxygen, transport, copper-glycoprotein with a di-copper active site found in the haemolymph of several marine and terrestrial invertebrates belonging to the phyla Mollusca and Arthropoda. Haemocyanin exists in two distinct conformers: the T-conformer …